Dana-Farber’s Pathways and Philips suite of Oncology Informatics Solutions deliver best practices and clinical decision support for cancer care management

Amsterdam, the Netherlands and Boston, Mass. – Royal Philips (NYSE: PHG, AEX: PHIA), a global leader in health technology, today announced it will be implementing Clinical Pathways from the Dana-Farber Cancer Institute, a leading center of cancer research and treatment, and founding member of the NCI-designated Dana-Farber/Harvard Cancer Center, to establish best practices in cancer care. The Dana-Farber Clinical Pathways will be deployed through the Philips IntelliSpace Oncology Platform, providing clinical decision support to physicians via a patient-centric solution. The implementation will help oncologists quickly reach the most appropriate cancer treatments for patients, based on the unified view of the patient across diagnostic modalities and the embedded knowledge of Clinical Pathways, and can be delivered through existing EHR platforms.

Cancer is an incredibly complex set of diseases and the amount of information and treatment options available can be challenging to cope with for oncologists. Philips will leverage Dana-Farber Clinical Pathways to effectively map cancer patients to the appropriate treatment options. Philips will power this clinical decision support through its oncology informatics suite, which integrates radiology, pathology, genomics and EHR data to support pathways to scale precision medicine.

For example, in patients whose chronic myelogenous leukemia is progressing after first-line therapy, Dana-Farber Pathways helps physicians sort through over a dozen different possible resistance mutations and a handful of targeted therapies with very different side effect profiles to find the most appropriate treatment for that particular patient.

“Every cancer patient deserves the best possible care. Our Clinical Pathways provide physicians with the most current, evidence-based best practices so that all patients may be treated with the same high standard of care,” said Dr. Laurie H. Glimcher, CEO, Dana-Farber. “Cancer medicine is changing rapidly, and physicians are tasked with interpreting massive amounts of new information generated from publications and clinical trials. Through this collaboration with Philips, we can help them choose the best possible treatment for patients based on specific information and the deep experience of our clinicians.”

“Patient-centric care is key to providing the best cancer treatment to those who need it,” said Frans van Houten, CEO of Royal Philips. “Together with our partners, we aim to optimize the flow of patient information from various sources and streamline care delivery through the adoption of best practices. By leveraging the unrivaled clinical knowledge and expertise incorporated in Dana-Farber Clinical Pathways, Philips’ oncology informatics suite of technologies can assist in providing the most effective care for people based on their genome, and then put it in the hand of doctors through clinical decision support.”

Dana-Farber Clinical Pathways will provide best practices from the institute’s leading oncologists and extensive care teams to support cancer treatment, leveraging the integrated diagnostic capabilities of Philips IntelliSpace Oncology, a cloud-based precision medicine platform that integrates information across different clinical domains. As cancer treatment changes regularly, updates will be made to each pathway several times a year.

For more information on Philips collaboration with Dana-Farber, the full portfolio of Philips oncology informatics solutions and Philips’ presence at the American Society of Clinical Oncology (ASCO) Annual Meeting, visit Booth #7159 on the exhibit floor, and follow @PhilipsLiveFrom for #ASCO18 updates throughout the event.

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Philips showcases end to end oncology informatics solutions at ASCO 2018

Seamless digital pathology, genomics and tumor surveillance technology support pathways to scale precision medicine programs

Philips solutions leverage integrative diagnostics and deep insights to help assist oncologists with the information they need to drive confident paths to treatment

Amsterdam, the Netherlands – Royal Philips (NYSE: PHG, AEX: PHIA), a global leader in health technology, will showcase a broad range of integrated oncology solutions, including IntelliSpace Genomics and IntelliSpace Oncology, to help support and scale precision medicine programs to assist oncologists with treatment decisions at the 2018 American Society of Clinical Oncology Annual Meeting (ASCO) in Chicago, Ill.

Individualized, precision medicine is key in reaching accurate diagnoses and effective treatment plans for cancer patients, but should be informed through accepted best practices to maximize quality of care and outcomes. These patients require constant vigilance and collaboration across multiple domains, and oncologists can face challenges when trying to compile a complete picture of all necessary patient information to support the decision making process. With new technologies and solutions like IntelliSpace Oncology, a cloud-based platform integrating information across different clinical domains such as radiology, pathology, EHR systems and genomics, all key patient data is seamlessly incorporated into one location, to provide a clear, intuitive view of patient status in its disease and state context that facilitates data-driven clinical decision support.

“Philips is committed to empowering clinicians with successful oncology care pathways by providing them with the necessary solutions to do so,” said Louis Culot, general manager, Oncology Informatics, Philips. “As a leader in oncology diagnostics, informatics and therapeutics, Philips is always striving to find ways to make life better for those suffering from cancer, as well as those responsible for delivering that care.”

Continued partnerships with industry leaders on precision medicine
Philips is dedicated to addressing healthcare’s quadruple aim of better clinical outcomes, lower costs and improved patient and staff satisfaction through connected care technologies and partnerships with industry leaders. To that end, during ASCO17, Philips announced that it teamed up with NAVICAN, an Intermountain Healthcare Company, to accelerate the delivery of precision medicine to health systems worldwide. In the Philips Booth (#7159) at ASCO 2018, NAVICAN will demonstrate its TheraMap™ offering, a comprehensive end-to-end solution for precision medicine integrated at the point-of-care. In addition to NGS test results, NAVICAN’s TheraMap report includes expert therapy recommendations prioritized by medical oncologists and access to experienced nurse navigators to help patients and their caregivers get the precision therapy they need as soon as possible. In a previously published study, NAVICAN’s approach demonstrated doubling of progression-free and overall survival, as well as an average 21% reduction in weekly healthcare costs [1].

Covering detection through treatment decision and surveillance
At ASCO18, Philips will spotlight specific, end-to-end oncology solutions to empower data-driven clinical decision support driving clinical, operational and financial benefits across the following key areas:

Integrative Diagnostics:
• IntelliSpace Genomics, a cloud-based precision medicine platform, automates genomic analysis for more precise diagnostics to inform therapy options and clinical trials. The solution also provides automated end-to-end workflows and customizable knowledgebase and report generation, while also improving data safety and security.
• IntelliSpace Portal, an advanced visualization tool, supports the clinical workflow across the cancer care continuum, including the ability to assess lung nodules over time with the CT Lung Nodule Assessment, monitor tumor progression and treatment response with Multimodality Tumor Tracking, and prepare for complex oncology procedures with 3D modeling.
• IntelliSite Pathology, the first and currently only digital pathology solution in the U.S. to be marketed for primary diagnostic use, can aid pathologists to view and diagnose digital images of surgical pathology slides to streamline workflow and extend collaboration with the aim of increasing diagnostic confidence.

Deeper Insights:
• IntelliSpace Oncology assists with complex treatment decisions, including hundreds of FDA-approved anti-cancer agents, and provides daily patient care insights based on evidence-based decision tools to promote guidelines adherence.
• OncoSignal, a proprietary test system unique to Philips, measures signaling pathway activity in individual tumor samples to predict targeted therapy response. Test results could help to select the best systemic treatment, allowing for simplified testing, better stratification and new therapy options [2].

Confident path:
• The Dana-Farber Clinical Pathways will be deployed through the Philips IntelliSpace Oncology Platform, providing clinical decision support to physicians via a patient-centric solution. The implementation will help oncologists quickly reach the most appropriate cancer treatments for patients, based on the unified view of the patient across diagnostic modalities and the embedded knowledge of Clinical Pathways, and can be delivered through existing EHR platforms.
• To drive efficient and personalized patient specific radiotherapy treatment planning workflows, Philips has integrated Sun Nuclear’s PlanIQ technology into Pinnacle to create Pinnacle Auto-Planning with PlanIQ. This allows for better management of risk with automated, template driven planning workflows that can also assist in MACRA and ACR accreditation initiatives and drive continuous quality improvement with benchmarking tools.
• TissueMark, uses deep learning AI technology to accurately identify tumor samples and estimate tumor percentages. This empowers pathologists and labs to enhance the quality of macrodissection and ultimately aids in reducing costs in molecular testing caused by insufficient tumor input [3].

During ASCO 2017, Philips announced it had signed an agreement with Memorial Sloan Kettering Cancer center to develop new methodologies and informatics approaches for advanced precision diagnostics to help uncover the drivers for cancer at the single-cell level. In 2018, Philips has signed additional agreements with Dana-Farber and Perlmutter Cancer Center at NYU Langone Health.

For more information on the full portfolio of Philips integrated oncology solutions and Philips’ presence at the American Society of Clinical Oncology Annual Meeting, visit Booth #7159 on the exhibit floor, and follow @PhilipsLiveFrom for #ASCO18 updates throughout the event.

References
[1] Haslem, D S, Chakravarthy I, et al. “Precision Oncology in Advanced Cancer Patients Improves Overall Survival with Lower Weekly Healthcare Costs.” Advances in Pediatrics., U.S. National Library of Medicine, 2 Feb. 2018.
[2] OncoSignal is available for Research Use Only and not for use in Diagnostic Procedures (not for use in clinical settings).
[3] TissueMark is not intended for diagnostic, monitoring or therapeutic purpose or in any other manner for regular medical practice.